Defenders James Collins and Patrice Evra are schedule to leave West Ham as sloon as their contracts expire on 30 June.
Collins, who turns 35 in August, played 214 times in two spells with the club.
Evra, 37, played just five games after being handed a short-term deal by David Moyes, who has now left the Hammers.
A statement on the club website read: “We would like to place on record our sincere thanks for the outstanding service James has given West Ham United down the years.”