The Norwegian has made the job look easy since arriving in December to steady the ship.
Manchester United are still yet to taste defeat in the Premier League since he took charge, winning nine of their 11 contests.
Under Jose Mourinho, the Red Devils began to make a mess of home matches that looked straight forward on paper.
Now United cannot afford to drop any more points as the race for fourth spot hots up.
Getting the best from Lukaku
Romelu Lukaku comes into the clash with the Saints on the back of a brace against Crystal Palace.
The Belgian’s United career is currently at a crossroads and it looks as if the next few months may decide his future.
It’s crucial that in the absence of a number of forwards, Solskjaer plays to Lukaku’s strengths which is leaving him space to run into.
The former Everton man has shown he is capable of being effective from the right but this weekend’s attack should be shaped around the £75million signing and letting him roam free through the middle.
Cut the Saints supply
Under Ralph Hasenhuttl, Southampton have regularly used three at the back.
While it’s stopped them leaking goals, it’s also come at the expense of the free-flowing attacking football the club has played over years in the Premier League.
Solskjaer should instruct his players to press high and force errors, it takes a lot of character to come to Old Trafford and play out from the back successfully.
Alexis Sanchez’s tenacity could prove handy if United are prepared to pin the opposition in their own half.
Persist with Fred
The £52m signing must be very poor in training given the lack of opportunities he’s received since Solskjaer took over.
But he started against Crystal Palace on Wednesday and now it’s all about finding rhythm if he is to stay at the club beyond this season.
With Ander Herrera and Nemanja Matic expected to remain sidelined, it’s a good chance for the Brazilian to keep his place.
Sometimes players can play their way out of bad form and if Pep Guardiola was so keen on signing the midfielder, he deserves a chance to do so.