Riding high on a series of masterclass performances, City is looking to baptize Schalke tonight as they did Chelsea a few days ago.
However, in a statement to the press, Manager Pep Guardiola has divulged that prolific striker Gabriel Jesus and stone-wall defender Jone Stones will miss out on the game due to injuries.
The German club will be hosting the reigning Premier League champions in the first leg of their round of 16 Champions League encounter.
John Stones has been ruled out because of a groin issue, while Gabriel Jesus is suffering from a hamstring injury.
None of the players have recovered in time for this tough Champions League game.
Kickoff is 11pm tonight.