Luis Suarez is set miss two weeks with a knee problem amid a series of fresh blows for injury-hit Barcelona.
Star striker Suarez played the full match in the 1-1 weekend draw at Atletico Madrid but will undergo stem-cell treatment to address an issue in his right knee.
The 31-year-old is out of the Champions League visit to PSV on Wednesday and could remain unavailable until after the derby against Espanyol in LaLiga on December 8.
Netherlands goalkeeper Jasper Cillessen will join Suarez on the sidelines for up to three weeks after reporting a thigh issue in the warm-up on Saturday.
Rafinha and Roberto sustained anterior cruciate ligament and hamstring injuries respectively on a costly outing at the Wanda Metropolitano, where Barca equalised late through Ousmane Dembele.
